Uteroplacental arterial changes related to interstitial trophoblast migration in early human pregnancy

R Pijnenborg, JM Bland, WB Robertson, I Brosens - Placenta, 1983 - Elsevier
Morphometric and statistical techniques were used to assess the relation of myometrial
interstitial trophoblast to the uteroplacental vasculature in 27 intact hysterectomy specimens
ranging from 8 to 18 weeks' gestation. It was found that the volume density of cytotrophoblast
in the myometrium and in particular the proximity of such trophoblast to the placental bed
spiral arteries correlated significantly with morphological alterations in these vessels. The
changes included swelling of endothelium, hypertrophy of individual medial smooth muscle …