[HTML][HTML] p204 is required for the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes: its expression is activated by the cardiac Gata4 …
B Ding, C Liu, Y Huang, RP Hickey, J Yu… - Journal of Biological …, 2006 - ASBMB
Among 10 adult mouse tissues tested, the p204 protein levels were highest in heart and
skeletal muscle. We described previously that the MyoD-inducible p204 protein is required
for the differentiation of cultured murine C2C12 skeletal muscle myoblasts to myotubes.
Here we report that p204 was also required for the differentiation of cultured P19 murine
embryonal carcinoma stem cells to beating cardiac myocytes. As shown by others, this
process can be triggered by dimethyl sulfoxide (DMSO). We established that DMSO induced …
skeletal muscle. We described previously that the MyoD-inducible p204 protein is required
for the differentiation of cultured murine C2C12 skeletal muscle myoblasts to myotubes.
Here we report that p204 was also required for the differentiation of cultured P19 murine
embryonal carcinoma stem cells to beating cardiac myocytes. As shown by others, this
process can be triggered by dimethyl sulfoxide (DMSO). We established that DMSO induced …