Dietary approaches to stop hypertension diet and activity to limit gestational weight: maternal offspring metabolics family intervention trial, a technology enhanced …
L Van Horn, A Peaceman, M Kwasny, E Vincent… - American journal of …, 2018 - Elsevier
American journal of preventive medicine, 2018•Elsevier
Introduction Technology-enhanced antenatal diet and lifestyle intervention could prevent
excess gestational weight gain and benefit mother and child. Study design A randomized
clinical trial. Setting/participants Overweight and obese ethnically diverse pregnant women
in Chicago, Illinois, were enrolled between October 2012 and December 2015, with
antenatal data collection completed by July 2016. Analysis was completed June 2017.
Intervention Participants were randomized when their fetus was gestational age 16 weeks to …
excess gestational weight gain and benefit mother and child. Study design A randomized
clinical trial. Setting/participants Overweight and obese ethnically diverse pregnant women
in Chicago, Illinois, were enrolled between October 2012 and December 2015, with
antenatal data collection completed by July 2016. Analysis was completed June 2017.
Intervention Participants were randomized when their fetus was gestational age 16 weeks to …
Introduction
Technology-enhanced antenatal diet and lifestyle intervention could prevent excess gestational weight gain and benefit mother and child.
Study design
A randomized clinical trial.
Setting/participants
Overweight and obese ethnically diverse pregnant women in Chicago, Illinois, were enrolled between October 2012 and December 2015, with antenatal data collection completed by July 2016. Analysis was completed June 2017.
Intervention
Participants were randomized when their fetus was gestational age 16 weeks to dietitian-led Dietary Approaches to Stop Hypertension diet and physical activity coaching that was received as three individual and six group counseling sessions by phone and webinar. A commercially available smartphone application was used for self-monitoring diet and physical activity. Telephone, text message prompts, and e-mail reminders encouraged adherence and website viewing. Usual-care, “web-watcher” participants were e-mailed biweekly newsletters and publicly available maternity website links.
Main outcome measures
The primary outcome was gestational weight gain measured at baseline, 24 weeks, and 35.0–36.6 weeks. Secondary outcomes included weekly rate of gestational weight gain, newborn anthropometrics, maternal diet quality, physical activity, and blood pressure.
Results
Among 281 participants randomized (n=140 in intervention, n=141 in usual care, BMI 25 to <40, and age range 18–40 years), 37% were non-white and 274 completed antenatal data collection (n=139 in the intervention group and n=135 in the usual-care group). Gestational weight gain differed significantly by intervention group (difference, 1.7kg, p=0.01) and rate of weight gain was 0.4 (SD=0.2) vs 0.5 (SD=0.2) kg/week. No significant differences were noted in birth weight, percentage body fat, or adverse pregnancy outcomes, but more cesarean sections (55 [40%] vs 37 [27%]) occurred among the intervention group.
Conclusions
Technology-enhanced Dietary Approaches to Stop Hypertension diet and lifestyle intervention resulted in significantly less total gestational weight gain over 35 weeks with no adverse infant outcomes. Nutrient quality improved without an adverse impact on rate of prematurity. Increased cesarean delivery requires further exploration. The National Academy of Medicine goals were not achieved by the majority of participants. Obesity prevention preconception is needed.
Trial registration
This study is registered at www.clinicaltrials.gov NCT01631747.
Elsevier