Adaptive humoral immune responses in the airways are mediated by B cells and plasma
cells that express highly evolved and specific receptors and produce immunoglobulins of
most isotypes. In some cases, such as autoimmune diseases or inflammatory diseases
caused by excessive exposure to foreign antigens, these same immune cells can cause
disease by virtue of overly vigorous responses. This review discusses the generation,
differentiation, signaling, activation, and recruitment pathways of B cells and plasma cells …