Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered.

SB Halstead, S Nimmannitya… - The Yale journal of …, 1970 - ncbi.nlm.nih.gov
SB Halstead, S Nimmannitya, SN Cohen
The Yale journal of biology and medicine, 1970ncbi.nlm.nih.gov
MATERIALS AND METHODS Patient selection, serologic methods, virus isolation and
identification techniques and definition ofprimary and secondary dengue antibody
responseshave been de-scribed.',','This report is based upon experience with 604
denguehemorrhagic fever patients: 400 admitted to Children's Hospital between April 19,
1962 and January 1, 1965 (CH Study); 123 admitted to the ThaiHemorrhagic Fever Ward in
July through September, 1964 (CRC Study), and 81 fatal hemorrhagic fever cases admitted …
MATERIALS AND METHODS Patient selection, serologic methods, virus isolation and identification techniques and definition ofprimary and secondary dengue antibody responseshave been de-scribed.',','
This report is based upon experience with 604 denguehemorrhagic fever patients: 400 admitted to Children's Hospital between April 19, 1962 and January 1, 1965 (CH Study); 123 admitted to the ThaiHemorrhagic Fever Ward in July through September, 1964 (CRC Study), and 81 fatal hemorrhagic fever cases admitted to other Bangkok hospitals in 1962-1964. All DHF patients who survived their infection had serologic evidence of recent dengue infection according to established criteria'and a discharge diagnosis of hemorrhagic fever. Included for some evaluations are 35 out-
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