[HTML][HTML] Heme Oxygenase-1 expression in M-CSF-polarized M2 macrophages contributes to LPS-induced IL-10 release
E Sierra-Filardi, MA Vega, P Sánchez-Mateos… - Immunobiology, 2010 - Elsevier
The shift between pro-inflammatory (M1) and anti-inflammatory (M2) states of macrophage
polarization allows the resolution of inflammatory processes as well as the maintenance of a
basal anti-inflammatory environment in tissues continuously exposed to harmless antigens
(eg, lung and gut). To identify markers for the anti-inflammatory state of macrophages,
expression profiling was performed on human macrophages polarized by either GM-CSF or
M-CSF, which lead to the generation of TNF-α and IL-12p40-producing pro-inflammatory …
polarization allows the resolution of inflammatory processes as well as the maintenance of a
basal anti-inflammatory environment in tissues continuously exposed to harmless antigens
(eg, lung and gut). To identify markers for the anti-inflammatory state of macrophages,
expression profiling was performed on human macrophages polarized by either GM-CSF or
M-CSF, which lead to the generation of TNF-α and IL-12p40-producing pro-inflammatory …