Association between 7 years of intensive treatment of type 1 diabetes and long-term mortality

TJ Orchard, DM Nathan, B Zinman, P Cleary, D Brillon… - Jama, 2015 - jamanetwork.com
Importance Whether mortality in type 1 diabetes mellitus is affected following intensive
glycemic therapy has not been established. Objective To determine whether mortality
differed between the original intensive and conventional treatment groups in the long-term
follow-up of the Diabetes Control and Complications Trial (DCCT) cohort. Design, Setting,
and Participants After the DCCT (1983-1993) ended, participants were followed up in a
multisite (27 US and Canadian academic clinical centers) observational study …