Epigenetic control of macrophage polarization
O Takeuch, S Akira - European journal of immunology, 2011 - Wiley Online Library
O Takeuch, S Akira
European journal of immunology, 2011•Wiley Online LibraryEpigenetic control of gene expression is critical for cellular differentiation and development.
Macrophage development, polarization and activation are also controlled by DNA and
histone modifications. This Viewpoint summarizes the recent findings on the role of histone
modifications regulating macrophage polarization toward M1 and M2 subtypes.
Macrophage development, polarization and activation are also controlled by DNA and
histone modifications. This Viewpoint summarizes the recent findings on the role of histone
modifications regulating macrophage polarization toward M1 and M2 subtypes.
Abstract
Epigenetic control of gene expression is critical for cellular differentiation and development. Macrophage development, polarization and activation are also controlled by DNA and histone modifications. This Viewpoint summarizes the recent findings on the role of histone modifications regulating macrophage polarization toward M1 and M2 subtypes.
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