Mesenchymal stem cells: Stem cell therapy perspectives for type 1 diabetes
L Vija, D Farge, JF Gautier, P Vexiau, C Dumitrache… - Diabetes & …, 2009 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent non-haematopoietic progenitor cells that
are being explored as a promising new treatment for tissue regeneration. Although their
immunomodulatory properties are not yet completely understood, their low immunogenic
potential together with their effects on immune response make them a promising therapeutic
tool for severe refractory autoimmune diseases. Type 1 diabetes is characterized by T cell-
mediated autoimmune destruction of pancreatic β cells. While insulin replacement …
are being explored as a promising new treatment for tissue regeneration. Although their
immunomodulatory properties are not yet completely understood, their low immunogenic
potential together with their effects on immune response make them a promising therapeutic
tool for severe refractory autoimmune diseases. Type 1 diabetes is characterized by T cell-
mediated autoimmune destruction of pancreatic β cells. While insulin replacement …