Abstract Evaluation of tissues is a common and important aspect of translational research
studies. Labeling techniques such as immunohistochemistry can stain cells/tissues to
enhance identification of specific cell types, cellular activation states, and protein
expression. While qualitative evaluation of labeled tissues has merit, use of semiquantitative
and quantitative scoring approaches can greatly enhance the rigor of the tissue data.
Adhering to key principles for reproducible scoring can enhance the quality and …