[PDF][PDF] Off-the-shelf CAR-NK cells for cancer immunotherapy
CAR-T therapy has shown great success treating blood cancers, but drawbacks include high
manufacturing costs and potentially fatal toxicities such as cytokine release syndrome. In this
issue of Cell Stem Cell, Li et al.(2018) describe how engineered iPSC-derived NK cells
armed with NK-tailored CAR constructs (CAR-iPSC-NK cells) provide better options for anti-
cancer immunotherapy.
manufacturing costs and potentially fatal toxicities such as cytokine release syndrome. In this
issue of Cell Stem Cell, Li et al.(2018) describe how engineered iPSC-derived NK cells
armed with NK-tailored CAR constructs (CAR-iPSC-NK cells) provide better options for anti-
cancer immunotherapy.
CAR-T therapy has shown great success treating blood cancers, but drawbacks include high manufacturing costs and potentially fatal toxicities such as cytokine release syndrome. In this issue of Cell Stem Cell, Li et al. (2018) describe how engineered iPSC-derived NK cells armed with NK-tailored CAR constructs (CAR-iPSC-NK cells) provide better options for anti-cancer immunotherapy.
cell.com