With the increasing prevalence of Clostridium difficile infection among hospitalized patients,
a clear understanding of C. difficile epidemiology is needed to evaluate current prevention
policies, and to create new and effective policies. To determine the epidemiology of C.
difficile, the most sensitive methods for detection of C. difficile are required. The purpose of
this study was to systematically assess multiple methods to determine the most sensitive
method to recover C. difficile from stool and rectal swabs. Stool samples from healthy …