Allergic diseases and asthma: a major global health concern

R Pawankar, GW Canonica, ST Holgate… - Current opinion in …, 2012 - journals.lww.com
Current opinion in allergy and clinical immunology, 2012journals.lww.com
The prevalence of allergic diseases and asthma is increasing worldwide, particularly in low
and middle-income countries. Moreover, the complexity and severity of allergic diseases,
including asthma, continue to increase especially in children and young adults, who are
bearing the greatest burden of these trends. In order to address this major global challenge
that threatens health and economies alike, it is important to have a global action plan that
includes partnerships involving different stakeholders from low-income, middle-income, and …
The prevalence of allergic diseases and asthma is increasing worldwide, particularly in low and middle-income countries. Moreover, the complexity and severity of allergic diseases, including asthma, continue to increase especially in children and young adults, who are bearing the greatest burden of these trends. In order to address this major global challenge that threatens health and economies alike, it is important to have a global action plan that includes partnerships involving different stakeholders from low-income, middle-income, and high-income countries. Allergic diseases include life-threatening anaphylaxis, food allergies, certain forms of asthma, rhinitis, conjunctivitis, angioedema, urticaria, eczema, eosinophilic disorders, including eosinophilic esophagitis, and drug and insect allergies. Globally, 300 million people suffer from asthma and about 200–250 million people suffer from food allergies [1]. One-tenth of the population suffers from drug allergies and 400 million from rhinitis [1]. Moreover, allergic diseases commonly occur together in the same individual, one disease with the other. This requires an integrated approach to diagnosis and treatment and greater awareness of the underlying causes among family physicians, patients as well as specialists.
A recent report from the World Allergy Organization, the WAO White Book on Allergy [1], summarizes the burden of allergic diseases worldwide, the risk factors, impact on quality of life of patients, morbidity, mortality, their socio-economic consequences, recommended treatment strategies, future therapies, and the cost–benefit analyses of care services. For instance, asthma prevalence is rising in several high as well as low-income and middle-income countries, and the prevalence and impact of allergic diseases continue to grow. According to the World Health Organization, the number of patients having asthma is 300 million and with the rising trends it is expected to increase to 400 million by 2025. Patients with asthma and allergic diseases have a reduced quality of life. According to the World Health Organization,
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