[HTML][HTML] Wound repair: role of immune–epithelial interactions

G Leoni, PA Neumann, R Sumagin, TL Denning… - Mucosal …, 2015 - Elsevier
The epithelium serves as a highly selective barrier at mucosal surfaces. Upon injury,
epithelial wound closure is orchestrated by a series of events that emanate from the
epithelium itself as well as by the temporal recruitment of immune cells into the wound bed.
Epithelial cells adjoining the wound flatten out, migrate, and proliferate to rapidly cover
denuded surfaces and re-establish mucosal homeostasis. This process is highly regulated
by proteins and lipids, proresolving mediators such as Annexin A1 protein and resolvins …