Teratoma generation in the testis capsule

SE Peterson, HT Tran, I Garitaonandia, S Han… - JoVE (Journal of …, 2011 - jove.com
Pluripotent stem cells (PSCs) have the unique characteristic that they can differentiate into
cells from all three germ layers. This makes them a potentially valuable tool for the treatment
of many different diseases. With the advent of induced pluripotent stem cells (iPSCs) and
continuing research with human embryonic stem cells (hESCs) there is a need for assays
that can demonstrate that a particular cell line is pluripotent. Germline transmission has
been the gold standard for demonstrating the pluripotence of mouse embryonic stem cell …