The subarachnoid space as a site for precursor T cell proliferation and effector T cell selection in experimental autoimmune encephalomyelitis
T Shin, T Kojima, N Tanuma, Y Ishihara… - Journal of …, 1995 - Elsevier
To characterize the phenotype of inflammatory cells in the central nervous system (CNS) in
experimental autoimmune encephalomyelitis (EAE), Lewis rats were immunized with guinea
pig myelin basic protein and frozen sections of the spinal cord with EAE were examined
immunohistochemically using a panel of monoclonal antibodies against T cells and
adhesion molecules. In addition, double immunostaining was performed with glial and T
cells markers to examine the interaction between infiltrating T cells and reactive brain cells …
experimental autoimmune encephalomyelitis (EAE), Lewis rats were immunized with guinea
pig myelin basic protein and frozen sections of the spinal cord with EAE were examined
immunohistochemically using a panel of monoclonal antibodies against T cells and
adhesion molecules. In addition, double immunostaining was performed with glial and T
cells markers to examine the interaction between infiltrating T cells and reactive brain cells …