Insights into the chicken IgY with emphasis on the generation and applications of chicken recombinant monoclonal antibodies

W Lee, AS Atif, SC Tan, CH Leow - Journal of immunological methods, 2017 - Elsevier
The advantages of chicken (Gallus gallus domesticus) antibodies as immunodiagnostic and
immunotherapeutic biomolecules has only been recently recognized. Even so, chicken
antibodies remain less-well characterized than their mammalian counterparts. This review
aims at providing a current overview of the structure, function, development and generation
of chicken antibodies. Additionally, brief but comprehensive insights into current knowledge
pertaining to the immunogenetic framework and diversity-generation of the chicken …