Long-term use of aspirin and nonsteroidal anti-inflammatory drugs and risk of colorectal cancer
AT Chan, EL Giovannucci, JA Meyerhardt… - Jama, 2005 - jamanetwork.com
ContextRandomized trials of short-term aspirin use for prevention of recurrent colorectal
adenoma have provided compelling evidence of a causal relationship between aspirin and
colorectal neoplasia. However, data on long-term risk of colorectal cancer according to
dose, timing, or duration of therapy with aspirin and other nonsteroidal anti-inflammatory
drugs (NSAIDs) remain limited. ObjectiveTo examine the influence of aspirin and NSAIDs in
prevention of colorectal cancer. Design, Setting, and ParticipantsProspective cohort study of …
adenoma have provided compelling evidence of a causal relationship between aspirin and
colorectal neoplasia. However, data on long-term risk of colorectal cancer according to
dose, timing, or duration of therapy with aspirin and other nonsteroidal anti-inflammatory
drugs (NSAIDs) remain limited. ObjectiveTo examine the influence of aspirin and NSAIDs in
prevention of colorectal cancer. Design, Setting, and ParticipantsProspective cohort study of …