Adoptive transfer of immunity to hepatitis B virus after T cell-depleted allogeneic bone marrow transplantation

Y Ilan, A Nagler, R Adler, E Naparstek, R Or… - Hepatology, 1993 - journals.lww.com
Recipients of allogeneic bone marrow transplantation are pancytopenic for several weeks
and immunosuppressed for many months as a result of myeloablative therapy required to
eliminate the basic disease and to prevent allograft rejection. After bone marrow
transplantation, these patients remain profoundly immunosuppressed by the chemotherapy
and immunotherapy used as prophylaxis against graft-vs.-host disease, treatment of
established disease or both. These patients are usually dependent on multiple blood …