Role of T cell immunity in recovery from influenza virus infection
J Sun, TJ Braciale - Current opinion in virology, 2013 - Elsevier
Highlights•Local interaction between APCs and T cells controls influenza T cell
responses.•Effector T cells use multiple mechanisms to restrict influenza infection.•Target
cell types determine effector T cell activities in situ.•Nonconventional T cells help to clear
virus and limit tissue injury.Influenza virus infection has the potential to induce excess
pulmonary inflammation and massive tissue damage in the infected host. Conventional
CD4+ and CD8+ as well as nonconventional innate like T cells respond to infection and …
responses.•Effector T cells use multiple mechanisms to restrict influenza infection.•Target
cell types determine effector T cell activities in situ.•Nonconventional T cells help to clear
virus and limit tissue injury.Influenza virus infection has the potential to induce excess
pulmonary inflammation and massive tissue damage in the infected host. Conventional
CD4+ and CD8+ as well as nonconventional innate like T cells respond to infection and …