Regulation of hematopoiesis by chemokine family members

HE Broxmeyer - International journal of hematology, 2001 - Springer
International journal of hematology, 2001Springer
Chemokines, originally designated as chemoattractant cytokines, comprise a large family of
molecules that have been implicated in a number of different functions mediated through
chemokine receptors. Among these functions are regulatory roles in hematopoiesis that
encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor
cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of
myeloid progenitor cells.
Abstract
Chemokines, originally designated as chemoattractant cytokines, comprise a large family of molecules that have been implicated in a number of different functions mediated through chemokine receptors. Among these functions are regulatory roles in hematopoiesis that encompass effects on the proliferation, survival, and homing/migration of myeloid progenitor cells. This article reviews the field of chemokine regulation of hematopoiesis at the level of myeloid progenitor cells.
Springer