[HTML][HTML] Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activities
HE Broxmeyer, CH Kim - Experimental hematology, 1999 - Elsevier
The field of chemokine biology is a rapidly advancing one, with over 50 chemokines
identified that mediate their effects through one or more of 16 different chemokine receptors.
Chemokines, originally identified as chemotactic cytokines, manifest a number of functions,
including modulation of blood cell production at the level of hematopoietic stem/progenitor
cells and the directed movement of these early blood cells. This report reviews chemokines
and chemokine/receptor activities mainly in the context of hematopoietic cell regulation and …
identified that mediate their effects through one or more of 16 different chemokine receptors.
Chemokines, originally identified as chemotactic cytokines, manifest a number of functions,
including modulation of blood cell production at the level of hematopoietic stem/progenitor
cells and the directed movement of these early blood cells. This report reviews chemokines
and chemokine/receptor activities mainly in the context of hematopoietic cell regulation and …