Although several randomized controlled trials (RCTS) of surgically menopausal women
have provided evidence that estrogen protects aspects of memory, many cross-sectional
and longitudinal studies, including those from the RCT, the Women's Health Initiative
Memory Study (WHIMS), have reported inconsistent information with regard to the
relationship between estrogen and aspects of cognitive function. Although numerous
reasons could be offered to explain these discrepancies in research findings, recent …