[HTML][HTML] Subfertility, uterine hypoplasia, and partial progesterone resistance in mice lacking the Krüppel-like factor 9/basic transcription element-binding protein-1 …

RCM Simmen, RR Eason, JR McQuown, AL Linz… - Journal of Biological …, 2004 - ASBMB
Progesterone receptor (PR), a ligand-activated transcription factor, is a key regulator of
cellular proliferation and differentiation in reproductive tissues. The transcriptional activity of
PR is influenced by co-regulatory proteins typically expressed in a tissue-and cell-specific
fashion. We previously demonstrated that basic transcription element-binding protein-1
(BTEB1), a member of the Sp/Krüppel-like family of transcription factors, functionally
interacts with the two PR isoforms, PR-A and PR-B, to mediate progestin sensitivity of target …