Autophagy has recently elicited significant attention as a mechanism that either protects or
promotes cell death, although different autophagy pathways, and the cellular context in
which they occur, remain to be elucidated. We report a thorough cellular and biochemical
characterization of a novel selective autophagy that works as a protective cell response. This
new selective autophagy is activated in pancreatic acinar cells during pancreatitis-induced
vesicular transport alteration to sequester and degrade potentially deleterious activated …