NK cells and cancer: you can teach innate cells new tricks

MG Morvan, LL Lanier - Nature Reviews Cancer, 2016 - nature.com
Nature Reviews Cancer, 2016nature.com
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic
function that provide host defence against microbial infection and tumours. Here, we review
evidence for the role of NK cells in immune surveillance against cancer and highlight new
therapeutic approaches for targeting NK cells in the treatment of cancer.
Abstract
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic function that provide host defence against microbial infection and tumours. Here, we review evidence for the role of NK cells in immune surveillance against cancer and highlight new therapeutic approaches for targeting NK cells in the treatment of cancer.
nature.com