Differential expression of HLA-E, HLA-F, and HLA-G transcripts in human tissue
X Wei, HT Orr - Human immunology, 1990 - Elsevier
The data presented here demonstrated that the HLA-G class I gene is unique among the
members of the human class I gene family in that its expression is restricted to
extraembryonic tissues during gestation. Furthermore, the pattern of HLA-G expression in
these tissues changes as gestation proceeds. During first trimester HLA-G is expressed
within the placenta and not within the extravillous membrane. At term, the pattern of the HLA-
G expression is reversed, extravillous membrane expressed HLA-G while placenta does not …
members of the human class I gene family in that its expression is restricted to
extraembryonic tissues during gestation. Furthermore, the pattern of HLA-G expression in
these tissues changes as gestation proceeds. During first trimester HLA-G is expressed
within the placenta and not within the extravillous membrane. At term, the pattern of the HLA-
G expression is reversed, extravillous membrane expressed HLA-G while placenta does not …