[HTML][HTML] IL-33 promotes gastrointestinal allergy in a TSLP-independent manner
H Han, F Roan, LK Johnston, DE Smith, PJ Bryce… - Mucosal …, 2018 - Elsevier
Atopic dermatitis (AD) often precedes asthma and food allergy, indicating that epicutaneous
sensitization to allergens may be important in the induction of allergic responses at other
barrier surfaces. Thymic stromal lymphopoietin (TSLP) and interleukin (IL)-33 are two
cytokines that may drive type 2 responses in the skin; both are potential targets in the
treatment of allergic diseases. We tested the functional role of IL-33 and the interplay
between IL-33 and TSLP in mouse models of atopic march and gastrointestinal (GI) allergy …
sensitization to allergens may be important in the induction of allergic responses at other
barrier surfaces. Thymic stromal lymphopoietin (TSLP) and interleukin (IL)-33 are two
cytokines that may drive type 2 responses in the skin; both are potential targets in the
treatment of allergic diseases. We tested the functional role of IL-33 and the interplay
between IL-33 and TSLP in mouse models of atopic march and gastrointestinal (GI) allergy …
