[HTML][HTML] RBEL1 is a novel gene that encodes a nucleocytoplasmic Ras superfamily GTP-binding protein and is overexpressed in breast cancer
JA Montalbano, W Jin, MS Sheikh, Y Huang - Journal of biological …, 2007 - ASBMB
Rab family proteins are generally known as regulators of protein transport and trafficking. A
number of Rab proteins have been implicated in cancer development and/or progression.
Here we report the identification of a novel Rab-like protein, which we have named RBEL1
(Rab-like protein 1) for its higher similarity to the Rab subfamily members. We have
characterized two isoforms of RBEL1 including the predominant RBEL1A and the less
abundant RBEL1B that results from alternative splicing. Both isoforms harbor conserved N …
number of Rab proteins have been implicated in cancer development and/or progression.
Here we report the identification of a novel Rab-like protein, which we have named RBEL1
(Rab-like protein 1) for its higher similarity to the Rab subfamily members. We have
characterized two isoforms of RBEL1 including the predominant RBEL1A and the less
abundant RBEL1B that results from alternative splicing. Both isoforms harbor conserved N …