Immune rejection of organ transplants has life-threatening implications. It is believed that
allograft rejection is initiated by the activation of lymphocytes following recognition of donor
antigens, leading to generation of effector T lymphocytes, alloantibody production, and graft
infiltration by alloreactive cells. There is solid evidence that miRNAs are integral for
maintaining immune homeostasis and self-tolerance. A deeper understanding of the
regulation of the immune response by miRNAs could define new mechanisms for …