Experimental arthritis causes tumor necrosis factor-α-dependent infiltration of macrophages into rat dorsal root ganglia which correlates with pain-related behavior
GS von Banchet, MK Boettger, N Fischer, M Gajda… - PAIN®, 2009 - Elsevier
After peripheral nerve damage macrophages infiltrate the dorsal root ganglia (DRG) in
which cell bodies of lesioned neurons are located. However, infiltration of macrophages into
the DRGs was also reported in complete Freund's adjuvant (CFA)-induced inflammation
raising the question whether CFA inflammation induces nerve cell damage or whether
peripheral inflammation may also trigger macrophage infiltration into DRGs. Related
questions are, first, which signals trigger macrophage infiltration into DRGs and, second, is …
which cell bodies of lesioned neurons are located. However, infiltration of macrophages into
the DRGs was also reported in complete Freund's adjuvant (CFA)-induced inflammation
raising the question whether CFA inflammation induces nerve cell damage or whether
peripheral inflammation may also trigger macrophage infiltration into DRGs. Related
questions are, first, which signals trigger macrophage infiltration into DRGs and, second, is …