[PDF][PDF] Pausing on the path to robustness
Heat-shock proteins (Hsps) maintain homeostasis by assisting protein folding, and the
transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et
al.(2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA
polymerase pausing, contributing to rapid, robust induction of many genes.
transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et
al.(2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA
polymerase pausing, contributing to rapid, robust induction of many genes.
Heat-shock proteins (Hsps) maintain homeostasis by assisting protein folding, and the transcriptional regulation of Hsp-coding genes has long been under study. Sawarkar et al. (2012) now report in Cell that Hsp90 is itself a transcriptional regulator required for RNA polymerase pausing, contributing to rapid, robust induction of many genes.
cell.com