BCG-osis and tuberculosis in a child with chronic granulomatous disease

J Bustamante, G Aksu, G Vogt… - Journal of allergy and …, 2007 - Elsevier
A few known primary immunodeficiencies confer predisposition to clinical disease caused
by weakly virulent mycobacteria, such as BCG vaccines (regional disease, known as BCG-
itis, or disseminated disease, known as BCG-osis), or more virulent mycobacteria, such as
Mycobacterium tuberculosis (pulmonary and disseminated tuberculosis). We investigated
the clinical and genetic features of a 12-year-old boy with both recurrent BCG-osis and
disseminated tuberculosis. The patient's phagocytic cells produced no O2−. A hemizygous …