Acute antibody-mediated rejection after lung transplantation
CA Witt, JP Gaut, RD Yusen, DE Byers, JA Iuppa… - The Journal of Heart and …, 2013 - Elsevier
Background Antibody-mediated rejection (AMR) after lung transplantation remains
enigmatic, and there is no consensus on the characteristic clinical, immunologic and
histologic features. Methods We performed a retrospective, single-center cohort study and
identified cases of acute AMR based on the presence of circulating donor-specific human
leukocyte antigen (HLA) antibodies (DSA), histologic evidence of acute lung injury, C4d
deposition and clinical allograft dysfunction. Results We identified 21 recipients with acute …
enigmatic, and there is no consensus on the characteristic clinical, immunologic and
histologic features. Methods We performed a retrospective, single-center cohort study and
identified cases of acute AMR based on the presence of circulating donor-specific human
leukocyte antigen (HLA) antibodies (DSA), histologic evidence of acute lung injury, C4d
deposition and clinical allograft dysfunction. Results We identified 21 recipients with acute …