Exogenous fatty acids provide substrates for energy production and biogenesis of the
cytoplasmic membrane, but they also enhance cellular signaling during cancer cell
proliferation. However, it remains controversial whether dietary fatty acids are correlated with
tumor progression. In this study, we demonstrate that increased Src kinase activity is
associated with high-fat diet–accelerated progression of prostate tumors and that Src
kinases mediate this pathological process. Moreover, in the in vivo prostate regeneration …