The action of thyroid hormones (thyroxine, T4; triiodothyronine, T3) on brain development
and function is gaining renewed interest. It has been known for many years that thyroid
hormones are very important in mammalian brain maturation, influencing many aspects
related to neural cell migration, differentiation, and signaling. In the last 10 years, genes
regulated by thyroid hormones have been identified in the rodent brain, and understanding
of the role of thyroid hormone nuclear receptors has been facilitated with the analysis of the …