[HTML][HTML] Identification and profiling of novel α1A-adrenoceptor-CXC chemokine receptor 2 heteromer
We have provided the first evidence for specific heteromerization between the α 1A-
adrenoceptor (α 1A AR) and CXC chemokine receptor 2 (CXCR2) in live cells. α 1A AR and
CXCR2 are both expressed in areas such as the stromal smooth muscle layer of the
prostate. By utilizing the G protein-coupled receptor (GPCR) heteromer identification
technology on the live cell-based bioluminescence resonance energy transfer (BRET) assay
platform, our studies in human embryonic kidney 293 cells have identified norepinephrine …
adrenoceptor (α 1A AR) and CXC chemokine receptor 2 (CXCR2) in live cells. α 1A AR and
CXCR2 are both expressed in areas such as the stromal smooth muscle layer of the
prostate. By utilizing the G protein-coupled receptor (GPCR) heteromer identification
technology on the live cell-based bioluminescence resonance energy transfer (BRET) assay
platform, our studies in human embryonic kidney 293 cells have identified norepinephrine …