[HTML][HTML] Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles
S Weilner, V Keider, M Winter, E Harreither… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
S Weilner, V Keider, M Winter, E Harreither, B Salzer, F Weiss, E Schraml, P Messner…
Aging (Albany NY), 2016•ncbi.nlm.nih.govAging results in a decline of physiological functions and in reduced repair capacities, in part
due to impaired regenerative power of stem cells, influenced by the systemic environment. In
particular osteogenic differentiation capacity (ODC) of mesenchymal stem cells (MSCs) has
been shown to decrease with age, thereby contributing to reduced bone formation and an
increased fracture risk.
due to impaired regenerative power of stem cells, influenced by the systemic environment. In
particular osteogenic differentiation capacity (ODC) of mesenchymal stem cells (MSCs) has
been shown to decrease with age, thereby contributing to reduced bone formation and an
increased fracture risk.
Abstract
Aging results in a decline of physiological functions and in reduced repair capacities, in part due to impaired regenerative power of stem cells, influenced by the systemic environment. In particular osteogenic differentiation capacity (ODC) of mesenchymal stem cells (MSCs) has been shown to decrease with age, thereby contributing to reduced bone formation and an increased fracture risk.
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