[HTML][HTML] Interferon consensus sequence-binding protein is constitutively expressed and differentially regulated in the ocular lens
W Li, CN Nagineni, H Ge, B Efiok… - Journal of Biological …, 1999 - ASBMB
Interferon signaling is mediated by STATs and interferon regulatory factor (IRF) families of
transcription factors. Ten distinct IRFs have been described and most are expressed in a
variety of cells except for interferon consensus sequence-binding protein (ICSBP) and
lymphoid-specific IRF/Pip that are thought to be exclusively expressed in lymphoid cells. We
show here for the first time that ICSBP is constitutively and inducibly expressed in the mouse
lens. In contrast to lymphoid cells with exclusive expression of ICSBP in the nucleus, ICSBP …
transcription factors. Ten distinct IRFs have been described and most are expressed in a
variety of cells except for interferon consensus sequence-binding protein (ICSBP) and
lymphoid-specific IRF/Pip that are thought to be exclusively expressed in lymphoid cells. We
show here for the first time that ICSBP is constitutively and inducibly expressed in the mouse
lens. In contrast to lymphoid cells with exclusive expression of ICSBP in the nucleus, ICSBP …