[PDF][PDF] Two strings in one bow: PD-1 negatively regulates via co-receptor CD28 on T cells

J Krueger, CE Rudd - Immunity, 2017 - cell.com
J Krueger, CE Rudd
Immunity, 2017cell.com
The identity of PD-1 dependency on other receptors and signaling has been unclear. In a
recent issue of Science, Hui et al.(2017) and Kamphorst et al.(2017) now show that CD28
expression is a target of PD-1-associated phosphatases and is needed for T cell expansion
in anti-PD-1 immunotherapy.
The identity of PD-1 dependency on other receptors and signaling has been unclear. In a recent issue of Science, Hui et al. (2017) and Kamphorst et al. (2017) now show that CD28 expression is a target of PD-1-associated phosphatases and is needed for T cell expansion in anti-PD-1 immunotherapy.
cell.com