Regulation of type I procollagen and MMP-1 expression after single or repeated exposure to infrared radiation in human skin

MS Kim, YK Kim, KH Cho, JH Chung - Mechanisms of ageing and …, 2006 - Elsevier
Human skin is daily exposed to infrared (IR) radiation from natural sunlight. However, the
effects of IR irradiation on collagen metabolism have not been investigated in human skin in
vivo. Here, we examined whether single or repeated (three times a week for 4 weeks)
exposure to IR irradiation changes the expressions of type I procollagen and interstitial
collagenase (MMP-1). By using immunostaining, Western blotting, and semi-quantitative RT-
PCR, we analyzed the protein and mRNA levels of type I procollagen and MMP-1 in young …