[HTML][HTML] Lectin galactoside-binding soluble 3 binding protein (LGALS3BP) is a tumor-associated immunomodulatory ligand for CD33-related Siglecs
H Läubli, F Alisson-Silva, MA Stanczak… - Journal of Biological …, 2014 - ASBMB
Lectin galactoside-binding soluble 3 binding protein (LGALS3BP, also called Mac-2 binding
protein) is a heavily glycosylated secreted molecule that has been shown previously to be
up-regulated in many cancers and has been implicated in tumor metastatic processes, as
well as in other cell adhesion and immune functions. The CD33-related subset of sialic acid-
binding immunoglobulin-like lectins (Siglecs) consists of immunomodulatory molecules that
have recently been associated with the modulation of immune responses to cancer …
protein) is a heavily glycosylated secreted molecule that has been shown previously to be
up-regulated in many cancers and has been implicated in tumor metastatic processes, as
well as in other cell adhesion and immune functions. The CD33-related subset of sialic acid-
binding immunoglobulin-like lectins (Siglecs) consists of immunomodulatory molecules that
have recently been associated with the modulation of immune responses to cancer …
