[HTML][HTML] Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma
M Binsfeld, J Muller, V Lamour, K De Veirman… - Oncotarget, 2016 - ncbi.nlm.nih.gov
M Binsfeld, J Muller, V Lamour, K De Veirman, H De Raeve, A Bellahcène…
Oncotarget, 2016•ncbi.nlm.nih.govMultiple myeloma (MM) is a plasma cell malignancy characterized by the accumulation of
tumor cells in the bone marrow (BM) and is associated with immunosuppression,
angiogenesis and osteolysis. Myeloid-derived suppressor cells (MDSCs) represent a
heterogeneous population of immature, immunosuppressive myeloid cells that promote
tumor progression through different mechanisms.
tumor cells in the bone marrow (BM) and is associated with immunosuppression,
angiogenesis and osteolysis. Myeloid-derived suppressor cells (MDSCs) represent a
heterogeneous population of immature, immunosuppressive myeloid cells that promote
tumor progression through different mechanisms.
Abstract
Multiple myeloma (MM) is a plasma cell malignancy characterized by the accumulation of tumor cells in the bone marrow (BM) and is associated with immunosuppression, angiogenesis and osteolysis. Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of immature, immunosuppressive myeloid cells that promote tumor progression through different mechanisms.
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