The CD4+ CD25bright regulatory T cells and CTLA-4 expression in peripheral and decidual lymphocytes are down-regulated in human miscarriage
LP Jin, QY Chen, T Zhang, PF Guo, DJ Li - Clinical immunology, 2009 - Elsevier
The present study was undertaken to analyze the changes in the proportion of CD4+
CD25bright regulatory T (Treg) cells and the expression of costimulatory molecules, CTLA-4
and CD28, in the peripheral blood and deciduas in the setting of non-pregnancy, normal
early pregnancy and miscarriage. In this study, we showed that CD4+ CD25bright T cells
significantly increased in the peripheral of normal pregnancy compared to that of non-
pregnancy. The proportions of CD4+ CD25bright T cells in both peripheral blood and …
CD25bright regulatory T (Treg) cells and the expression of costimulatory molecules, CTLA-4
and CD28, in the peripheral blood and deciduas in the setting of non-pregnancy, normal
early pregnancy and miscarriage. In this study, we showed that CD4+ CD25bright T cells
significantly increased in the peripheral of normal pregnancy compared to that of non-
pregnancy. The proportions of CD4+ CD25bright T cells in both peripheral blood and …