Human vaginal histology in long-term users of the injectable contraceptive depot-medroxyprogesterone acetate

MV Bahamondes, S Castro, NM Marchi, M Marcovici… - Contraception, 2014 - Elsevier
Objectives Apparently, depot-medroxyprogesterone acetate (DMPA) increases a woman's
risk of acquiring HIV. The objective of this study was to test whether the vaginal mucosal
thickness and Langerhans cell counts were significantly different in long-term DMPA users
compared with women users of an intrauterine device (IUD) who had never used DMPA.
Study design Cross-sectional study. Twenty-three DMPA users were matched with 23
nonusers controlled for age, body mass index (BMI; kg/m 2), and duration of contraceptive …