Pembrolizumab treatment of a patient with xeroderma pigmentosum with disseminated melanoma and multiple nonmelanoma skin cancers.

KH Kraemer, D Tamura… - British Journal of …, 2018 - search.ebscohost.com
KH Kraemer, D Tamura, SG Khan
British Journal of Dermatology, 2018search.ebscohost.com
The article discusses the xeroderma pigmentosum (XP) which is a rare genodermatosis with
a high increased risk of skin cancer because of an inability to repair ultraviolet radiation-
induced deoxyribonucleic acid (DNA) damage. It states that patients at a median age of 9
years with untreated XP have developed skin cancer.
Abstract
The article discusses the xeroderma pigmentosum (XP) which is a rare genodermatosis with a high increased risk of skin cancer because of an inability to repair ultraviolet radiation-induced deoxyribonucleic acid (DNA) damage. It states that patients at a median age of 9 years with untreated XP have developed skin cancer.
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