Phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity in patients with inherited IFN-γR1 or IFN-γR2 deficiency

F Conti, WC Aragão Filho, C Prando… - Journal of Allergy and …, 2015 - jacionline.org
To the Editor: An understanding of protective immunity to mycobacterial infection is critical
for the development of effective strategies to control tuberculosis (TB), a major public health
problem worldwide. Mendelian susceptibility to mycobacterial disease (MSMD) is a rare
condition characterized by clinical disease caused by weakly virulent mycobacteria, such as
Mycobacterium bovis Bacille Calmette-Guérin (BCG) vaccines and nontuberculous,
environmental mycobacteria (OMIM209950). 1 Patients are also susceptible to M …