Pain Mechanisms: A New Theory: A gate control system modulates sensory input from the skin before it evokes pain perception and response.

R Melzack, PD Wall - Science, 1965 - science.org
R Melzack, PD Wall
Science, 1965science.org
The nature of pain has been the subject of bitter controversy since the turn of the'century (1).
There are currently two opposing theories of pain:(i) specificity theory, which holds that pain
is a specific modality like vision or hearing," with its own central and peripheral
apparatus"(2), and (ii) pattern theory, which maintains that the nerve impulse pattern for pain
is produced by intense stimulation of nonspecific receptors since" there are no specific fibers
and no specific endings"(3). Both theories derive from earlier concepts proposed by von …
The nature of pain has been the subject of bitter controversy since the turn of the'century (1). There are currently two opposing theories of pain:(i) specificity theory, which holds that pain is a specific modality like vision or hearing," with its own central and peripheral apparatus"(2), and (ii) pattern theory, which maintains that the nerve impulse pattern for pain is produced by intense stimulation of nonspecific receptors since" there are no specific fibers and no specific endings"(3). Both theories derive from earlier concepts proposed by von Frey (4) and Goldscheider (5) in 1894, and historically they are held to be mutually exclusive. Since it is our purpose here to propose a new theory, of pain mechanisms, we shall state eXiplicitly at the outset where we agree and disagree with specificity and pattern theories.
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