[HTML][HTML] The subtype-specific features of EVI1 and PRDM16 in acute myeloid leukemia

H Matsuo, S Goyama, Y Kamikubo, S Adachi - Haematologica, 2015 - ncbi.nlm.nih.gov
H Matsuo, S Goyama, Y Kamikubo, S Adachi
Haematologica, 2015ncbi.nlm.nih.gov
Both EVI1 and PRDM16 are highly expressed in hematopoietic stem cells. EVI1, but not
PRDM16, is up-regulated in some MLL-rearranged leukemia. HSC_BM: hematopoietic stem
cells from bone marrow; early HPC_BM: hematopoietic progenitor cells from bone marrow;
CMP: common myeloid progenitor cell; GMP: granulocyte monocyte progenitors; MEP:
megakaryocyte-erythroid progenitor cell; PM_BM: promyelocyte from bone marrow; MY_BM:
myelocyte from bone marrow; PMN_BM: polymorphonuclear cells from bone marrow; …
Both EVI1 and PRDM16 are highly expressed in hematopoietic stem cells. EVI1, but not PRDM16, is up-regulated in some MLL-rearranged leukemia. HSC_BM: hematopoietic stem cells from bone marrow; early HPC_BM: hematopoietic progenitor cells from bone marrow; CMP: common myeloid progenitor cell; GMP: granulocyte monocyte progenitors; MEP: megakaryocyte-erythroid progenitor cell; PM_BM: promyelocyte from bone marrow; MY_BM: myelocyte from bone marrow; PMN_BM: polymorphonuclear cells from bone marrow; PMN_PB: polymorphonuclear cells from peripheral blood; mDC: myeloid dendritic cells; pDC: plasmacytoid dendritic cells.
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