Enterotoxigenic Escherichia coli (ETEC) are a major cause of diarrheal illness in developing
countries, and perennially the most common cause of traveller's diarrhea. ETEC constitute a
diverse pathotype that elaborate heat-labile and/or heat-stable enterotoxins. Recent
molecular pathogenesis studies reveal sophisticated pathogen–host interactions that might
be exploited in efforts to prevent these important infections. While vaccine development for
these important pathogens remains a formidable challenge, extensive efforts that attempt to …